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Jean-Marc Riedinger Selected Research

7-ketocholesterol

1/20177-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD.
1/2017Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158N murine oligodendrocytes.
7/2015Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3).
7/2013Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes.
4/2010Iron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells.
1/2009Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis.

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Jean-Marc Riedinger Research Topics

Disease

11Neoplasms (Cancer)
12/2019 - 03/2005
10Breast Neoplasms (Breast Cancer)
12/2019 - 10/2005
3Neoplasm Metastasis (Metastasis)
01/2021 - 08/2017
2Mitochondrial Diseases (Mitochondrial Disease)
10/2018 - 01/2012
2Inflammation (Inflammations)
10/2018 - 04/2010
2Pathologic Complete Response
11/2016 - 12/2015
2Triple Negative Breast Neoplasms
11/2016 - 12/2015
2Neurodegenerative Diseases (Neurodegenerative Disease)
07/2015 - 07/2013
2Alzheimer Disease (Alzheimer's Disease)
01/2015 - 01/2012
2Atherosclerotic Plaque (Atheroma)
01/2009 - 05/2006
2Atherosclerosis
06/2007 - 04/2005
1Multiple Myeloma
10/2021
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
08/2021
1Cholangiocarcinoma
01/2021
1Colorectal Neoplasms (Colorectal Cancer)
01/2021
1Hepatocellular Carcinoma (Hepatoma)
01/2021
1Ductal Carcinoma
12/2019
1Body Weight (Weight, Body)
12/2019
1Thrombocytopenia (Thrombopenia)
02/2017
1Multiple Sclerosis
01/2017
1Demyelinating Diseases (Demyelinating Disease)
01/2017
1Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
01/2017
1Inborn Genetic Diseases (Disease, Hereditary)
01/2017
1Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
01/2015
1Dementia (Dementias)
01/2015
1Hodgkin Disease (Hodgkin's Disease)
01/2015
1Myocardial Infarction
02/2012
1Cardiovascular Diseases (Cardiovascular Disease)
04/2010
1Ovarian Epithelial Carcinoma
03/2007
1Carcinoma (Carcinomatosis)
10/2006
1Hyperlipidemias (Hyperlipidemia)
05/2006
1Disease Progression
06/2004
1Thyroid Neoplasms (Thyroid Cancer)
06/2004

Drug/Important Bio-Agent (IBA)

67-ketocholesterolIBA
01/2017 - 01/2009
5Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
10/2021 - 12/2015
5LipidsIBA
01/2015 - 06/2007
3Fatty Acids (Saturated Fatty Acids)IBA
10/2018 - 01/2015
3Glucose (Dextrose)FDA LinkGeneric
11/2016 - 01/2015
3Biomarkers (Surrogate Marker)IBA
11/2016 - 01/2015
3OxysterolsIBA
01/2009 - 05/2006
2Estrogen ReceptorsIBA
12/2019 - 08/2014
2Biological ProductsIBA
12/2019 - 04/2010
2human ERBB2 proteinIBA
04/2019 - 08/2014
2Proteins (Proteins, Gene)FDA Link
10/2018 - 01/2015
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2007 - 10/2006
2Caspase 3 (Caspase-3)IBA
10/2006 - 03/2005
2SurvivinIBA
10/2005 - 03/2005
1Indium-111IBA
08/2021
1Yttrium-90IBA
01/2021
1Blood Glucose (Blood Sugar)IBA
12/2019
1Phenobarbital (Luminal)FDA Link
04/2019
1Adenosine Triphosphate (ATP)IBA
10/2018
1EnzymesIBA
10/2018
1Cardiolipins (Cardiolipin)IBA
10/2018
1Indicators and Reagents (Reagents)IBA
10/2018
1PlasmalogensIBA
10/2018
1Messenger RNA (mRNA)IBA
10/2018
1Carcinoembryonic AntigenIBA
08/2017
1Edetic Acid (EDTA)FDA Link
02/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2017
1Docosahexaenoic AcidsIBA
01/2017
1Tocopherols (Tocopherol)IBA
01/2017
1hexacosanoic acidIBA
01/2015
1lignoceric acid (tetracosanoic acid)IBA
01/2015
1TubulinIBA
01/2015
1taxaneIBA
08/2014
1Trastuzumab (Herceptin)FDA Link
08/2014
1CholesterolIBA
07/2013
1AntioxidantsIBA
02/2012
1Trypan BlueFDA Link
01/2012
13,3'-dihexyl-2,2'-oxacarbocyanineIBA
01/2012
1IronIBA
04/2010
1Epirubicin (Ellence)FDA LinkGeneric
05/2007
1Docetaxel (Taxotere)FDA Link
05/2007
1Pharmaceutical PreparationsIBA
05/2007
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
05/2007
1Fluorouracil (Carac)FDA LinkGeneric
10/2006
1CytokinesIBA
05/2006
1C-Reactive ProteinIBA
05/2006
1LDL Lipoproteins (beta Lipoproteins)IBA
04/2005
1Inhibitor of Apoptosis ProteinsIBA
03/2005
1Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
06/2004
1ThyroglobulinFDA Link
06/2004

Therapy/Procedure

8Neoadjuvant Therapy
12/2019 - 10/2006
4Drug Therapy (Chemotherapy)
11/2016 - 10/2006
3Therapeutics
12/2019 - 06/2004
2Segmental Mastectomy (Lumpectomy)
04/2019 - 11/2016
1Microspheres (Microsphere)
01/2021
1Mastectomy (Mammectomy)
04/2019
1Secondary Prevention
02/2012
1Induction Chemotherapy
03/2007